Before taking this medicine

You should not use Levitra if you are allergic to vardenafil.

Taking Levitra with certain other medicines can cause a sudden and serious decrease in blood pressure. Do not take vardenafil if you also take riociguat (Adempas), or if you take a nitrate drug for chest pain or heart problems. Nitrates include nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Nitrates are also found in some recreational drugs such as amyl nitrate or nitrite (\\\"poppers\\\").

To make sure Levitra is safe for you, tell your doctor if you have:

•    heart disease, heart rhythm problems;

•    a recent history (in the past 6 months) of a heart attack, stroke, or congestive heart failure;

•    a personal or family history of Long QT syndrome;

•    high or low blood pressure;

•    seizures;

•    liver disease, kidney disease (or if you are on dialysis);

•    a blood cell disorder such as sickle cell anemia, multiple myeloma, or leukemia;

•    a bleeding disorder such as hemophilia;

•    a stomach ulcer;

•    hearing or vision problems, history of vision loss;

•    an eye disorder such as retinitis pigmentosa (an inherited condition of the eye);

•    a physical deformity of the penis (such as Peyronie\\\'s disease); or

•    if you have been told you should not have sexual intercourse for health reasons.

Although Levitra is not for use in women, this medication is not expected to be harmful to an unborn baby.

Although Levitra is not for use in women, it is not known whether this medicine passes into breast milk or if it could harm a nursing baby.

Usual Adult Dose for Erectile Dysfunction:

-Initial dose: 10 mg orally once a day, as needed, approximately 60 minutes before sexual activity. Increase to 20 mg or decrease to 5 mg based on efficacy and tolerability.

-Maximum dose: 20 mg once a day

Patients on stable alpha-blocker therapy:

-Initial dose: 5 mg orally once a day

Comments:

-Sexual stimulation is required for a response to treatment.

-A time interval between dosing should be considered when administering this drug concomitantly with alpha-blockers.

Use: Erectile dysfunction

Usual Geriatric Dose for Erectile Dysfunction:

65 years or older:

-Initial dose: 5 mg orally once a day, as needed, approximately 60 minutes before sexual activity

Comments: Sexual stimulation is required for a response to treatment.

Use: Erectile dysfunction

What happens if I miss a dose?

Since Levitra is used as needed, you are not likely to be on a dosing schedule.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Levitra?

Grapefruit and grapefruit juice may interact with vardenafil and lead to unwanted side effects. Avoid the use of grapefruit products while taking vardenafil.Drinking alcohol can increase certain side effects of Levitra.

Do not use any other drug to treat impotence unless your doctor tells you to.

Get emergency medical help if you have any signs of an allergic reaction to Levitra: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Levitra and get emergency medical help if you have sudden vision loss.

During sexual activity, if you become dizzy or nauseated, or have pain, numbness, or tingling in your chest, arms, neck, or jaw, stop and call your doctor right away. You could be having a serious side effect.

Stop using Levitra and call your doctor at once if you have:

•    vision changes;

•    ringing in your ears, or sudden hearing loss;

•    heart attack symptoms - chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating;

•    irregular heartbeat;

•    swelling in your hands, ankles, or feet;

•    shortness of breath;

•    a light-headed feeling, like you might pass out;

•    penis erection that is painful or lasts 4 hours or longer; or

•    seizure (convulsions).

Common Levitra side effects may include:

•    flushing (warmth, redness, or tingly feeling);

•    stuffy nose;

•    headache, dizziness;

•    upset stomach; or

•    back pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Do not take Levitra with similar medicines such as avanafil (Stendra), sildenafil (Viagra), or tadalafil (Cialis). These medicines also have other brand names (Adcirca, Revatio) that are used to treat a condition called pulmonary arterial hypertension.

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with Levitra, especially:

•    all other medications you use for erectile dysfunction;

•    an antibiotic - clarithromycin, erythromycin, telithromycin, and others;

•    antifungal medicine - itraconazole, ketoconazole, and others;

•    drugs to treat high blood pressure or a prostate disorder - alfuzosin, doxazosin, prazosin, silodosin, terazosin, tamsulosin;

•    heart rhythm medicine - amiodarone, dofetilide, disopyramide, dronedarone, procainamide, quinidine, sotalol; or

•    HIV/AIDS medicine - atazanavir, indinavir, ritonavir, saquinavir, and others.

This list is not complete. Other drugs may interact with vardenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Effect of Other Drugs on Vardenafil

In vitro studies

Studies in human liver microsomes showed that vardenafil is metabolized primarily by cytochrome P450 (CYP) isoforms 3A4/5, and to a lesser degree by CYP2C9. Therefore, inhibitors of these enzymes are expected to reduce vardenafil clearance.

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.